A Novel Nodal Enhancer Dependent on Pluripotency Factors and Smad2/3 Signaling Conditions a Regulatory Switch During Epiblast Maturation | Zendy

Costis Papanayotou | Zendy; Ataaillah Benhaddou | Zendy; Anne Camus | Zendy; Aitana Perea-Gómez | Zendy; Alice Jouneau | Zendy; Valérie Mezger | Zendy; Francina Langa | Zendy; Sascha Ott | Zendy; Délara SabéranDjoneidi | Zendy; Jérôme Collig | Zendy

Open Access

A Novel Nodal Enhancer Dependent on Pluripotency Factors and Smad2/3 Signaling Conditions a Regulatory Switch During Epiblast Maturation

Author(s) -

Costis Papanayotou,

Ataaillah Benhaddou,

Anne Camus,

Aitana Perea-Gómez,

Alice Jouneau,

Valérie Mezger,

Francina Langa,

Sascha Ott,

Délara SabéranDjoneidi,

Jérôme Collig

Publication year - 2014

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001890

Subject(s) - nodal signaling , nodal , epiblast , biology , enhancer , microbiology and biotechnology , gastrulation , embryo , genetics , embryogenesis , transcription factor , gene

HBE, a newly discovered enhancer element, mediates the influence of pluripotency factors and Activin/Nodal signaling on early Nodal expression in the mouse embryo, and controls the activation of later-acting Nodal enhancers.

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