The Retromer Complex Is Required for Rhodopsin Recycling and Its Loss Leads to Photoreceptor Degeneration | Zendy

Shiuan Wang | Zendy; Kai Li Tan | Zendy; Melina A. Agosto | Zendy; Bo Xiong | Zendy; Shinya Yamamoto | Zendy; Héctor Sandoval | Zendy; Manish Jaiswal | Zendy; Vafa Bayat | Zendy; Ke Zhang | Zendy; WuLin Charng | Zendy; Gabriela David | Zendy; Lita Duraine | Zendy; Kartik Venkatachalam | Zendy; Theodore G. Wensel | Zendy; Hugo J. Bellen | Zendy

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The Retromer Complex Is Required for Rhodopsin Recycling and Its Loss Leads to Photoreceptor Degeneration

Author(s) -

Shiuan Wang,

Kai Li Tan,

Melina A. Agosto,

Bo Xiong,

Shinya Yamamoto,

Héctor Sandoval,

Manish Jaiswal,

Vafa Bayat,

Ke Zhang,

WuLin Charng,

Gabriela David,

Lita Duraine,

Kartik Venkatachalam,

Theodore G. Wensel,

Hugo J. Bellen

Publication year - 2014

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001847

Subject(s) - retromer , endosome , endocytosis , microbiology and biotechnology , biology , rhodopsin , retinal degeneration , degeneration (medical) , mutant , retina , neuroscience , biochemistry , receptor , retinal , gene , intracellular , medicine , pathology

Rhodopsin recycling via the retromer, rather than degradation through lysosomes, can alleviate light-induced photoreceptor degeneration in Drosophila .

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