Open AccessUnisexual and Heterosexual Meiotic Reproduction Generate Aneuploidy and Phenotypic Diversity De Novo in the Yeast Cryptococcus neoformans
Author(s) -
Min Ni,
Marianna Feretzaki,
WenJun Li,
Anna Floyd-Averette,
Piotr A. Mieczkowski,
Fred S. Dietrich,
Joseph Heitman
Publication year - 2013
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001653
Subject(s) - biology , heterothallic , genetics , cryptococcus neoformans , mating type , ploidy , aneuploidy , sexual reproduction , phenotype , cryptococcus , phenotypic switching , chromosome , gene
Unisexual and heterosexual reproduction in the pathogenic yeast Cryptococcus neoformans enables de novo phenotypic and genotypic plasticity with frequent aneuploidy and rapid adaptation.
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