Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription | Zendy

Sulakshana P. Mukherjee | Zendy; Marcelo Behar | Zendy; Harry Birnbaum | Zendy; Alexander Hoffmann | Zendy; Peter E. Wright | Zendy; Gourisankar Ghosh | Zendy

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Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription

Author(s) -

Sulakshana P. Mukherjee,

Marcelo Behar,

Harry Birnbaum,

Alexander Hoffmann,

Peter E. Wright,

Gourisankar Ghosh

Publication year - 2013

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001647

Subject(s) - biology , transcription factor , enhancer , transcription (linguistics) , creb , creb binding protein , gene , genetics , p300 cbp transcription factors , protein–protein interaction , transcriptional regulation , binding site , microbiology and biotechnology , linguistics , philosophy , histone acetyltransferases

A structural and functional study delineates how the interaction between NF-κB subunit RelA and co-activator CBP/p300 helps drive transcription of NF-κB target genes.

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