Distributive Conjugal Transfer in Mycobacteria Generates Progeny with Meiotic-Like Genome-Wide Mosaicism, Allowing Mapping of a Mating Identity Locus | Zendy

Todd A. Gray | Zendy; Janet A. Krywy | Zendy; Jessica Harold | Zendy; Michael J. Palumbo | Zendy; Keith M. Derbyshire | Zendy

Open Access

Distributive Conjugal Transfer in Mycobacteria Generates Progeny with Meiotic-Like Genome-Wide Mosaicism, Allowing Mapping of a Mating Identity Locus

Author(s) -

Todd A. Gray,

Janet A. Krywy,

Jessica Harold,

Michael J. Palumbo,

Keith M. Derbyshire

Publication year - 2013

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001602

Subject(s) - biology , genetics , horizontal gene transfer , genome , locus (genetics) , genome evolution , mycobacterium smegmatis , gene , evolutionary biology , mycobacterium tuberculosis , medicine , tuberculosis , pathology

We find that genome-wide DNA transfer by conjugation in mycobacteria affords bacteria that reproduce by binary fission the same advantages of sexual reproduction, and may explain the genomic evolution of Mycobacterium tuberculosis .

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