Open AccessTranscription-Factor-Mediated DNA Looping Probed by High-Resolution, Single-Molecule Imaging in Live E. coli Cells
Author(s) -
Zach Hensel,
Xiaoli Weng,
Arvin Cesar Lagda,
Jie Xiao
Publication year - 2013
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001591
Subject(s) - biology , dna , transcription (linguistics) , transcription factor , circular bacterial chromosome , mutant , repressor , microbiology and biotechnology , bacteriophage , dna replication , genetics , gene , escherichia coli , philosophy , linguistics
A high-resolution, single-molecule study directly assesses the prevalence and dynamics of DNA looping in gene regulation in live E. coli cells.
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