Open AccessEvolution of Robustness and Cellular Stochasticity of Gene Expression
Author(s) -
Steven A. Frank
Publication year - 2013
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001578
Subject(s) - biology , robustness (evolution) , phenotype , gene expression , computational biology , gene , genetics , evolutionary biology , biological system
Recent measurements of gene expression show a lot of randomness between cells. Steven Frank proposes a theory in which robustness protects against the effects of randomness and so allows relaxed regulatory control and greater randomness to evolve.
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