Open AccessDampening the Signals Transduced through Hedgehog via MicroRNA miR-7 Facilitates Notch-Induced Tumourigenesis
Author(s) -
Vanina G. Da Ros,
Irene Gutiérrez-Pérez,
Dolors Ferrés-Marcó,
María Domínguez
Publication year - 2013
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001554
Subject(s) - smoothened , hedgehog , biology , hedgehog signaling pathway , notch signaling pathway , microbiology and biotechnology , microrna , imaginal disc , signal transduction , genetics , drosophila melanogaster , gene
Analysis of tumorigenesis in Drosophila reveals a tumor-suppressor role for Hedgehog signaling in the context of oncogenic Notch signaling.
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