Vascular Calcifying Progenitor Cells Possess Bidirectional Differentiation Potentials
Author(s) -
Hyun-Ju Cho,
HyunJai Cho,
Hojae Lee,
Myung-Kang Song,
JiYun Seo,
Yeon-Hee Bae,
JuYoung Kim,
HaeYoung Lee,
Whal Lee,
BonKwon Koo,
ByungHee Oh,
Young-Bae Park,
HyoSoo Kim
Publication year - 2013
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001534
Subject(s) - progenitor cell , biology , stem cell , calcification , bone marrow , cellular differentiation , progenitor , mesenchymal stem cell , osteocalcin , cancer research , pathology , endocrinology , microbiology and biotechnology , immunology , alkaline phosphatase , medicine , biochemistry , gene , enzyme
Calcifying progenitor cells in blood vessels have the potential to differentiate into cells that either promote calcium accumulation or reverse accumulation, and treatment with PPAR? can shift the direction of this differentiation.
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