Open AccessHAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors
Author(s) -
Michael V. Airola,
Nattakan Sukomon,
Dipanjan Samanta,
Peter P. Borbat,
Jack H. Freed,
Kylie J. Watts,
Brian R. Crane
Publication year - 2013
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001479
Subject(s) - hamp , biology , hamp domain , chemotaxis , biophysics , microbiology and biotechnology , receptor , signal transduction , protein structure , biochemistry , peptide sequence , inflammation , gene , hepcidin , immunology
How do cell-surface receptors transmit signals into cells? This study resolves how signal relay occurs through the HAMP domains of bacterial chemoreceptors by causing them to switch between two conformational states.
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