Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome | Zendy

Cong Cao | Zendy; Mengia S. Rioult-Pedotti | Zendy; Paolo Migani | Zendy; Crystal J. Yu | Zendy; Rakesh K. Tiwari | Zendy; Keykavous Parang | Zendy; Mark R. Spaller | Zendy; Dennis J. Goebel | Zendy; John Marshall | Zendy

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Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome

Author(s) -

Cong Cao,

Mengia S. Rioult-Pedotti,

Paolo Migani,

Crystal J. Yu,

Rakesh K. Tiwari,

Keykavous Parang,

Mark R. Spaller,

Dennis J. Goebel,

John Marshall

Publication year - 2013

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001478

Subject(s) - tropomyosin receptor kinase b , long term potentiation , biology , synaptic plasticity , arc (geometry) , microbiology and biotechnology , signal transduction , brain derived neurotrophic factor , postsynaptic density , angelman syndrome , dendritic spine , neuroscience , neurotrophic factors , endocrinology , medicine , receptor , biochemistry , hippocampal formation , gene , geometry , mathematics

Brain-derived neurotrophic factor signaling is defective in Angelman syndrome and can be rescued by disruption of Arc/PSD95 binding.

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