Open AccessLoss of FGF-Dependent Mesoderm Identity and Rise of Endogenous Retinoid Signalling Determine Cessation of Body Axis Elongation
Author(s) -
Isabel Olivera-Martínez,
Hidekiyo Harada,
Pamela A. Halley,
Kate G. Storey
Publication year - 2012
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001415
Subject(s) - brachyury , biology , fgf and mesoderm formation , mesoderm , microbiology and biotechnology , fibroblast growth factor , endocrinology , medicine , genetics , embryonic stem cell , receptor , gene
By analyzing cellular and molecular changes in key cell populations in the tailbud during embryogenesis, this work uncovers critical signaling events that determine vertebrate body length.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom