A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity | Zendy

Joshua Wollam | Zendy; Daniel B. Magner | Zendy; Lilia Magomedova | Zendy; Elisabeth Rass | Zendy; Yidong Shen | Zendy; Veerle Rottiers | Zendy; Bianca Habermann | Zendy; Carolyn L. Cummins | Zendy; Adam Antebi | Zendy

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A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity

Author(s) -

Joshua Wollam,

Daniel B. Magner,

Lilia Magomedova,

Elisabeth Rass,

Yidong Shen,

Veerle Rottiers,

Bianca Habermann,

Carolyn L. Cummins,

Adam Antebi

Publication year - 2012

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001305

Subject(s) - longevity , biology , nuclear receptor , hydroxysteroid dehydrogenase , hydroxysteroid dehydrogenases , dehydrogenase , caenorhabditis elegans , hydroxysteroid , microbiology and biotechnology , genetics , transcription factor , biochemistry , enzyme , gene

A multidisciplinary approach identifies novel biochemical activities involved in the synthesisof C. elegans bile acid-like steroids, which act as hormones that regulate sterol metabolism and longevity.

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