Mediator Acts Upstream of the Transcriptional Activator Gal4 | Zendy

Keven Ang | Zendy; Gary Ee | Zendy; Edwin Ang | Zendy; Elvin Koh | Zendy; Wee Leng Siew | Zendy; Yu Mun Chan | Zendy; Sabriur | Zendy; Yee Sun Tan | Zendy; Norbert Lehming | Zendy

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Mediator Acts Upstream of the Transcriptional Activator Gal4

Author(s) -

Keven Ang,

Gary Ee,

Edwin Ang,

Elvin Koh,

Wee Leng Siew,

Yu Mun Chan,

Sabriur,

Yee Sun Tan,

Norbert Lehming

Publication year - 2012

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1001290

Subject(s) - biology , mediator , mg132 , ubiquitin ligase , enhancer , upstream activating sequence , activator (genetics) , microbiology and biotechnology , ubiquitin , transcription factor , transcriptional regulation , mutant , regulation of gene expression , transcription (linguistics) , repressor , gene , biochemistry , linguistics , philosophy

We show that Mediator, a protein originally isolated on the basis of its ability to respond to transcriptional activators, and thought to be regulated by an activator, can also be the master that controls the activator.

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