Open AccessRole of the Gut Endoderm in Relaying Left-Right Patterning in Mice
Author(s) -
Manuel Viotti,
Lei Niu,
SongHai Shi,
AnnaKaterina Hadjantonakis
Publication year - 2012
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001276
Subject(s) - endoderm , biology , gastrulation , microbiology and biotechnology , nodal , anatomy , gap junction , morphogenesis , mesoderm , embryo , genetics , embryonic stem cell , embryogenesis , intracellular , gene
Analysis of Sox 17 mutant mice reveals that gap junction coupling across the gut endoderm of the embryo transmits the left-right asymmetric signal from the node to the site of asymmetric organogenesis in mice.
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