Open AccessRole of Pleiotropy in the Evolution of a Cryptic Developmental Variation in Caenorhabditis elegans
Author(s) -
Fabien Duveau,
Marie-Anne Félix
Publication year - 2012
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001230
Subject(s) - biology , genetics , caenorhabditis elegans , allele , caenorhabditis , pleiotropy , human evolutionary genetics , gene , genetic variation , phenotype , evolutionary biology , experimental evolution , balancing selection , phylogenetics
Using vulval phenotypes in Caenorhabditis elegans , the authors show that cryptic genetic variation can evolve through selection for pleiotropic effects that alter fitness, and identify a cryptic variant that has conferred enhanced fitness on domesticated worms under laboratory conditions.
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