Genetic Variation Shapes Protein Networks Mainly through Non-transcriptional Mechanisms
Author(s) -
Eric J. Foss,
Dragan Radulović,
Scott A. Shaffer,
David R. Goodlett,
Leonid Kruglyak,
Antonio Bedalov
Publication year - 2011
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001144
Subject(s) - biology , ribosome biogenesis , ribosomal protein , genetics , gene , proteome , genetic variation , ribosome , transcriptome , population , gene expression , rna , demography , sociology
Variation in the levels of co-regulated proteins that function within networks in an outbred yeast population is not driven by variation in the corresponding transcripts.
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