A Novel Sperm-Delivered Toxin Causes Late-Stage Embryo Lethality and Transmission Ratio Distortion in C. elegans
Author(s) -
Hannah S. Seidel,
Michael Ailion,
JiaLing Li,
Alexander van Oudenaarden,
Matthew V. Rockman,
Leonid Kruglyak
Publication year - 2011
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1001115
Subject(s) - biology , embryo , sperm , genetics , caenorhabditis elegans , microbiology and biotechnology , ubiquitin ligase , ectopic expression , gene , ubiquitin
A sperm-delivered toxin and an embryo-expressed antidote form a co-adapted gene complex in C. elegans that promotes its own transmission to the detriment of organisms carrying it.
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