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Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver
Author(s) -
Guillaume Rey,
François Cesbron,
Jacques Rougemont,
Hans Reinke,
Michael Brunner,
Félix Naef
Publication year - 2011
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000595
Subject(s) - biology , circadian clock , circadian rhythm , zeitgeber , chromatin immunoprecipitation , genetics , transcription factor , per1 , microbiology and biotechnology , transcriptional regulation , clock , gene , promoter , gene expression , endocrinology
Temporal mapping during a circadian day of binding sites for the BMAL1 transcription factor in mouse liver reveals genome-wide daily rhythms in DNA binding and uncovers output functions that are controlled by the circadian oscillator.

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