Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver
Author(s) -
Guillaume Rey,
François Cesbron,
Jacques Rougemont,
Hans Reinke,
Michael Brunner,
Félix Naef
Publication year - 2011
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000595
Subject(s) - biology , circadian clock , circadian rhythm , zeitgeber , chromatin immunoprecipitation , genetics , transcription factor , per1 , microbiology and biotechnology , transcriptional regulation , clock , gene , promoter , gene expression , endocrinology
Temporal mapping during a circadian day of binding sites for the BMAL1 transcription factor in mouse liver reveals genome-wide daily rhythms in DNA binding and uncovers output functions that are controlled by the circadian oscillator.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom