Open AccessA Promiscuous DNA Packaging Machine from Bacteriophage T4
Author(s) -
Zhihong Zhang,
Vishal I. Kottadiel,
Reza Vafabakhsh,
Li Dai,
Yann R. Chemla,
Taekjip Ha,
Venigalla B. Rao
Publication year - 2011
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000592
Subject(s) - capsid , biology , dna , bacteriophage , molecular motor , genome , biophysics , molecular machine , computational biology , microbiology and biotechnology , genetics , virus , gene , escherichia coli
Packaged viral genome can be removed from bacteriophage T4 capsid and the capsid refilled with any double-stranded DNA, single or multiple molecules, using a powerful ATP-fueled DNA packaging machine.
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