Prox1 Regulates the Notch1-Mediated Inhibition of Neurogenesis
Author(s) -
Valeria Kaltezioti,
Georgia Kouroupi,
Maria Oikonomaki,
Evangelia Mantouvalou,
Αθανάσιος Στεργιόπουλος,
Aristidis Charonis,
Hermann Rohrer,
Rebecca Matsas,
Panagiotis Politis
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000565
Subject(s) - neurogenesis , biology , notch signaling pathway , proneural genes , hes1 , microbiology and biotechnology , neural stem cell , transcription factor , repressor , neural tube , progenitor cell , neuroscience , stem cell , signal transduction , gene , genetics , embryo
During development of the spinal cord, Prox1 controls the balance between proliferation and differentiation of neural progenitor cells via suppression of Notch1 gene expression.
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