A Genetic and Functional Relationship between T Cells and Cellular Proliferation in the Adult Hippocampus
Author(s) -
GuoJen Huang,
Adrian L. Smith,
Daniel H.D. Gray,
Cormac Cosgrove,
Benjamin H. Singer,
Andrew Edwards,
Stuart Sim,
Jack M. Parent,
Alyssa Johnsen,
Richard Mott,
Diane Mathis,
Paul Klenerman,
Christophe Benoist,
Jonathan Flint
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000561
Subject(s) - neurogenesis , biology , subgranular zone , dentate gyrus , hippocampus , gene knockout , cd8 , microbiology and biotechnology , subventricular zone , genetics , immunology , neural stem cell , neuroscience , stem cell , antigen , gene
A large correlation between variation in T cell subsets and hippocampal neurogenesis suggests that the immune system has an unexpectedly large influence on the brain.
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