Open AccessCo-Evolution of Transcriptional Silencing Proteins and the DNA Elements Specifying Their Assembly
Author(s) -
Oliver A. Zill,
Devin R. Scannell,
Lenny Teytelman,
Jasper Rine
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000550
Subject(s) - biology , saccharomyces cerevisiae , chromatin , genetics , dna , conserved sequence , gene silencing , yeast , gene , base sequence
As shown by genetic assays in Saccharomyces interspecies hybrids, the co-evolution of heterochromatin assembly proteins with silencer elements allows transcriptional silencing functions to be maintained in rapidly evolving regions of the genome.
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