Open AccessThe Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation
Author(s) -
Julien Moretti,
Patricia Chastagner,
Stefano Gastaldello,
Sara Farrah Heuss,
Annette M.G. Dirac,
René Bernards,
Maria G. Masucci,
Alain Israël,
Christel Brou
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000545
Subject(s) - microbiology and biotechnology , deubiquitinating enzyme , notch signaling pathway , biology , ubiquitin , ubiquitin ligase , signal transduction , biochemistry , gene
The translation initiation factor complex eIF3f has an intrinsic deubiquitinase activity and regulates the Notch signaling pathway.
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