A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export | Zendy

Thomas Wild | Zendy; Péter Horváth | Zendy; Emanuel Wyler | Zendy; Barbara Widmann | Zendy; Lukas Badertscher | Zendy; Ivo Zemp | Zendy; Karol Kozak | Zendy; Gábor Csúcs | Zendy; Elsebet Lund | Zendy; Ulrike Kutay | Zendy

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A Protein Inventory of Human Ribosome Biogenesis Reveals an Essential Function of Exportin 5 in 60S Subunit Export

Author(s) -

Thomas Wild,

Péter Horváth,

Emanuel Wyler,

Barbara Widmann,

Lukas Badertscher,

Ivo Zemp,

Karol Kozak,

Gábor Csúcs,

Elsebet Lund,

Ulrike Kutay

Publication year - 2010

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1000522

Subject(s) - eukaryotic small ribosomal subunit , eukaryotic large ribosomal subunit , biology , eukaryotic ribosome , ribosome biogenesis , ribosomal protein , microbiology and biotechnology , nuclear export signal , protein subunit , ran , ribosome , ribosomal rna , genetics , rna , cell nucleus , gene , nucleus

A systematic search for human ribosome biogenesis factors shows conservation of many aspects of eukaryotic ribosome synthesis with the well-studied process in yeast and identifies an export route of 60S subunits that is specific for higher eukaryotes.

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