Open AccessWRAP53 Is Essential for Cajal Body Formation and for Targeting the Survival of Motor Neuron Complex to Cajal Bodies
Author(s) -
Salah Mahmoudi,
Sofia Henriksson,
Irene Weibrecht,
Stephen A. Smith,
Ola Söderberg,
Staffan Strömblad,
Klas G. Wiman,
Marianne Farnebo
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000521
Subject(s) - biology , interstitial cell of cajal , cajal body , motor neuron , anatomy , neuroscience , spinal cord , immunohistochemistry , genetics , gene , rna , rna splicing , immunology
The WRAP53 protein regulates the formation and maintenance of Cajal bodies (nuclear sub-organelles), as well as directs the recruitment of nuclear factors to Cajal bodies.
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