Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development
Author(s) -
James J. Collins,
Xiaowen Hou,
Elena V. Romanova,
Bramwell G. Lambrus,
Claire Miller,
Amir Saberi,
Jonathan V. Sweedler,
Phillip A. Newmark
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000509
Subject(s) - biology , planarian , flatworm , prohormone convertase , prohormone , neuropeptide , genetics , microbiology and biotechnology , hormone , endocrinology , regeneration (biology) , zoology , receptor
Genomic/peptidomic analyses of the planarian Schmidtea mediterranea identifies >200 neuropeptides and uncovers a conserved neuropeptide required for proper maturation and maintenance of the reproductive system.
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