Cortical Overexpression of Neuronal Calcium Sensor-1 Induces Functional Plasticity in Spinal Cord Following Unilateral Pyramidal Tract Injury in Rat | Zendy

Ping K. Yip | Zendy; LiangFong Wong | Zendy; T. A. Sears | Zendy; Rafael J. YáñezMuñoz | Zendy; Stephen B. McMahon | Zendy

Open Access

Cortical Overexpression of Neuronal Calcium Sensor-1 Induces Functional Plasticity in Spinal Cord Following Unilateral Pyramidal Tract Injury in Rat

Author(s) -

Ping K. Yip,

LiangFong Wong,

T. A. Sears,

Rafael J. YáñezMuñoz,

Stephen B. McMahon

Publication year - 2010

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1000399

Subject(s) - biology , pyramidal tracts , spinal cord , corticospinal tract , neuroscience , neurite , neuroprotection , forelimb , sprouting , spinal cord injury , neuroplasticity , axon , central nervous system , anatomy , medicine , biochemistry , botany , diffusion mri , magnetic resonance imaging , in vitro , radiology

Overexpression of neuronal calcium sensor 1 in cortical neurons can help restore axonal plasticity and regeneration following axonal injury in adult rats, and can also improve behavioral function.

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