Open AccessSegment-Specific Neuronal Subtype Specification by the Integration of Anteroposterior and Temporal Cues
Author(s) -
Daniel Karlsson,
Magnus Baumgardt,
Stefan Thor
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000368
Subject(s) - hox gene , biology , neuroblast , lineage (genetic) , neuroscience , vertebrate , gene , genetics , neurogenesis , transcription factor
To address the question of how neuronal diversity is achieved throughout the CNS, this study provides evidence of modulation of neural progenitor cell “output” along the body axis by integration of local anteroposterior and temporal cues.
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