Open AccessAn Excitatory Loop with Astrocytes Contributes to Drive Neurons to Seizure Threshold
Author(s) -
Marta GómezGonzalo,
Gabriele Losi,
Angela Chiavegato,
Micaela Zonta,
Mario Cammarota,
Marco Brondi,
Francesco Vetri,
Laura Uva,
Tullio Pozzan,
Marco de Curtis,
Gian Michele Ratto,
Giorgio Carmignoto
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000352
Subject(s) - biology , excitatory postsynaptic potential , neuroscience , loop (graph theory) , epilepsy , inhibitory postsynaptic potential , mathematics , combinatorics
Studies in rodent brain slices suggest that seizures in focal epilepsies are sustained and propagated by the reciprocal interaction between neurons and astroglial cells
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