Open AccessBinding Site Turnover Produces Pervasive Quantitative Changes in Transcription Factor Binding between Closely Related Drosophila Species
Author(s) -
Robert K. Bradley,
Xiaoyong Li,
Cole Trapnell,
Stuart M. Davidson,
Lior Pachter,
Hou Cheng Chu,
Leath A. Tonkin,
Mark D. Biggin,
Michael B. Eisen
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000343
Subject(s) - biology , transcription factor , drosophila melanogaster , genetics , evolutionary biology , dna binding site , binding site , gene , gene expression , promoter
Genome-wide comparison of transcription factor binding between related Drosophila species highlights how sequence changes affect the biochemical events that underlie animal development.
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