Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes
Author(s) -
Casper C. Hoogenraad,
Ioana Popa,
Kensuke Futai,
Emma Sanchez-Martinez,
Phebe S. Wulf,
Thijs van Vlijmen,
Bjorn Dortland,
Viola Oorschot,
Roland Govers,
Maria Monti,
Albert J. R. Heck,
Morgan Sheng,
Judith Klumperman,
Holger Rehmann,
Dick Jaarsma,
Lukas C. Kapitein,
Peter van der Sluijs
Publication year - 2010
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000283
Subject(s) - endosome , biology , endocytic cycle , rab , microbiology and biotechnology , grasp , effector , transport protein , neuroscience , endocytosis , receptor , gtpase , biochemistry , computer science , intracellular , programming language
The neuronal protein GRASP-1 is shown to be a key molecule controlling endosomal trafficking and thereby regulating synapse integrity and synaptic plasticity.
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