Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster | Zendy

Sandra Goetze | Zendy; Ermir Qeli | Zendy; Christian Mosimann | Zendy; An Staes | Zendy; Bertran Gerrits | Zendy; Bernd Roschitzki | Zendy; Sonali Mohanty | Zendy; Eva Niederer | Zendy; Endre Laczkó | Zendy; Evy Timmerman | Zendy; Vinzenz Lange | Zendy; Ernst Hafen | Zendy; Ruedi Aebersold | Zendy; Joël Vandekerckhove | Zendy; Konrad Basler | Zendy; Christian H. Ahrens | Zendy; Kris Gevaert | Zendy; Erich Brunner | Zendy

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Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster

Author(s) -

Sandra Goetze,

Ermir Qeli,

Christian Mosimann,

An Staes,

Bertran Gerrits,

Bernd Roschitzki,

Sonali Mohanty,

Eva Niederer,

Endre Laczkó,

Evy Timmerman,

Vinzenz Lange,

Ernst Hafen,

Ruedi Aebersold,

Joël Vandekerckhove,

Konrad Basler,

Christian H. Ahrens,

Kris Gevaert,

Erich Brunner

Publication year - 2009

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1000236

Subject(s) - acetylation , biology , drosophila melanogaster , biochemistry , amino acid , function (biology) , peptide sequence , schneider 2 cells , genetics , gene , rna , rna interference

A new study reveals a functional rule for N-terminal acetylation in higher eukaryotes called the (X)PX rule and describes a generic method that prevents this modification to allow the study of N-terminal acetylation in any given protein.

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