Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins | Zendy

Raffi Tonikian | Zendy; Xiaofeng Xin | Zendy; Christopher P. Toret | Zendy; David Gfeller | Zendy; Christiane Landgraf | Zendy; Simona Panni | Zendy; Serena Paoluzi | Zendy; Luisa Castagnoli | Zendy; Bridget Currell | Zendy; Somasekar Seshagiri | Zendy; Haiyuan Yu | Zendy; Barbara Winsor | Zendy; Marc Vidal | Zendy; Mark Gerstein | Zendy; Gary D. Bader | Zendy; Rudolf Volkmer | Zendy; Gianni Cesareni | Zendy; David G. Drubin | Zendy; Philip M. Kim | Zendy; Sachdev S. Sidhu | Zendy; Charles Boone | Zendy

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Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins

Author(s) -

Raffi Tonikian,

Xiaofeng Xin,

Christopher P. Toret,

David Gfeller,

Christiane Landgraf,

Simona Panni,

Serena Paoluzi,

Luisa Castagnoli,

Bridget Currell,

Somasekar Seshagiri,

Haiyuan Yu,

Barbara Winsor,

Marc Vidal,

Mark Gerstein,

Gary D. Bader,

Rudolf Volkmer,

Gianni Cesareni,

David G. Drubin,

Philip M. Kim,

Sachdev S. Sidhu,

Charles Boone

Publication year - 2009

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1000218

Subject(s) - interactome , biology , endocytosis , sh3 domain , yeast , computational biology , domain (mathematical analysis) , protein–protein interaction , genetics , gene , signal transduction , proto oncogene tyrosine protein kinase src , cell , mathematical analysis , mathematics

A genome-scale specificity and interaction map for yeast SH3 domain-containing proteins reveal how family members show selective binding to target proteins and predicts the dynamic localization of new candidate endocytosis proteins.

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