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Exploration of Uncharted Regions of the Protein Universe
Author(s) -
Lukasz Jaroszewski,
Zhanwen Li,
Sanjeev Krishna,
Constantina Bakolitsa,
John Wooley,
Ashley M. Deacon,
Ian A. Wilson,
Adam Godzik
Publication year - 2009
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000205
Subject(s) - biology , genome , evolutionary biology , computational biology , genetics , function (biology) , gene , encode
Determination of first protein structures, from hundreds of families of unknown function, have shown that divergence, rather than novelty, is the dominant force that shapes the evolution of the protein universe.

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