Open AccessGeneration of Functional Eyes from Pluripotent Cells
Author(s) -
Andrea S. Viczian,
Eduardo Solessio,
Yung Lyou,
Michael E. Zuber
Publication year - 2009
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000174
Subject(s) - biology , induced pluripotent stem cell , embryonic stem cell , retinal , microbiology and biotechnology , retina , cell type , stem cell , anatomy , multipotent stem cell , progenitor cell , neuroscience , cell , genetics , biochemistry , gene
The directed differentiation of pluripotent cells into specific cell-types is a major hurdle in regenerative medicine. This study shows the eye field transcription factor factors can direct pluripotent cells into functioning frog eyes.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom