Natural Killer Cell Signal Integration Balances Synapse Symmetry and Migration | Zendy

Fiona J. Culley | Zendy; M. J. Johnson | Zendy; J. Henry Evans | Zendy; Sunil Kumar | Zendy; Rupert Crilly | Zendy; Juan Casasbuenas | Zendy; Tim Schnyder | Zendy; Maryam Mehrabi | Zendy; Mahendra P. Deonarain | Zendy; Dmitry S. Ushakov | Zendy; Véronique M. Braud | Zendy; Günter Roth | Zendy; Roland Brock | Zendy; Karsten Köhler | Zendy; Daniel M. Davis | Zendy

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Natural Killer Cell Signal Integration Balances Synapse Symmetry and Migration

Author(s) -

Fiona J. Culley,

M. J. Johnson,

J. Henry Evans,

Sunil Kumar,

Rupert Crilly,

Juan Casasbuenas,

Tim Schnyder,

Maryam Mehrabi,

Mahendra P. Deonarain,

Dmitry S. Ushakov,

Véronique M. Braud,

Günter Roth,

Roland Brock,

Karsten Köhler,

Daniel M. Davis

Publication year - 2009

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1000159

Subject(s) - biology , nkg2d , inhibitory postsynaptic potential , lamellipodium , microbiology and biotechnology , immunological synapse , cell migration , receptor , cell , natural killer cell , neuroscience , immune system , t cell , immunology , cytotoxic t cell , biochemistry , t cell receptor , in vitro

Imaging immune surveillance by natural killer (NK) cells has revealed that integration of activating and inhibitory signals determines whether or not NK cells stop to kill the target cell or retain a migratory configuration.

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