Lineage-Specific Biology Revealed by a Finished Genome Assembly of the Mouse
Author(s) -
Deanna M. Church,
Leo Goodstadt,
LaDeana W. Hillier,
Michael C. Zody,
Steve Goldstein,
Xinwe She,
Carol J. Bult,
Richa Agarwala,
Joshua L. Cherry,
Michael DiCuccio,
Wratko Hlavina,
Yuri Kapustin,
Peter Meric,
Donna Maglott,
Zoë Birtle,
Ana Claudia Marques,
Tina Graves,
Shiguo Zhou,
Brian Teague,
Konstantinos Potamousis,
Christopher Churas,
Michael Place,
Jill Herschleb,
Ron Runnheim,
Daniel K. Forrest,
James AmosLandgraf,
David C. Schwartz,
Ze Cheng,
Kerstin LindbladToh,
Evan E. Eichler,
Chris P. Ponting
Publication year - 2009
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000112
Subject(s) - biology , genome , genetics , gene , lineage (genetic) , transposable element , sequence assembly , shotgun sequencing , whole genome sequencing , genome evolution , human genome , computational biology , population , genome project , reference genome , coding region , gene expression , demography , transcriptome , sociology
A finished clone-based assembly of the mouse genome reveals extensive recent sequence duplication during recent evolution and rodent-specific expansion of certain gene families. Newly assembled duplications contain protein-coding genes that are mostly involved in reproductive function.
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