Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells | Zendy

Mark E. Burkard | Zendy; John Maciejowski | Zendy; Verónica Rodríguez-Bravo | Zendy; Michael Repka | Zendy; Drew M. Lowery | Zendy; Karl R. Clauser | Zendy; Chao Zhang | Zendy; Kevan M. Shokat | Zendy; Steven A. Carr | Zendy; Michael B. Yaffe | Zendy; Prasad V. Jallepalli | Zendy

Open Access

Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

Author(s) -

Mark E. Burkard,

John Maciejowski,

Verónica Rodríguez-Bravo,

Michael Repka,

Drew M. Lowery,

Karl R. Clauser,

Chao Zhang,

Kevan M. Shokat,

Steven A. Carr,

Michael B. Yaffe,

Prasad V. Jallepalli

Publication year - 2009

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.1000111

Subject(s) - cytokinesis , rhoa , biology , microbiology and biotechnology , cleavage furrow , plk1 , anaphase , aurora b kinase , cell division , signal transduction , cell cycle , biochemistry , cell

Self-regulated movement of Polo-like kinase 1 to the midzone of the mitotic spindle initiates a local signaling cascade that activates the cell division machinery at the cell's equator.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research