Open AccessMutation Patterns in the Human Genome: More Variable Than Expected
Author(s) -
Laurent Duret
Publication year - 2009
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.1000028
Subject(s) - biology , genome , genetics , human genome , evolutionary biology , mutation , computational biology , variable (mathematics) , gene , mathematical analysis , mathematics
Why are some genomic positions more mutable than others? The identification of cryptic mutation hotspots in the human genome indicates that the determinants of mutation rates are more complex than anticipated.
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