Open AccessUnravelling the Bcl-2 Apoptosis Code with a Simple Model System
Author(s) -
Gorka Basáñez,
J. Marie Hardwick
Publication year - 2008
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.0060154
Subject(s) - biology , programmed cell death , microbiology and biotechnology , multicellular organism , apoptosis , autophagy , bcl 2 family , mitochondrion , embryonic stem cell , intracellular , cell , genetics , gene
Using defined lipids and purified proteins, Billen et al. offer a new model to reconcile the two currently opposing models for how Bcl-2 family member interactions regulate cell death.
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