Open AccessMitochondrial Cell Death Control in Familial Parkinson Disease
Author(s) -
Guido Kroemer,
Klas Blomgren
Publication year - 2007
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.0050206
Subject(s) - biology , disease , parkinson's disease , genetics , mitochondrial dna , evolutionary biology , gene , pathology , medicine
Many sporadic cases of Parkinsons disease have mutations in the PINK protein kinase, whose substrate is now revealed to be a protein that protects mitochondria from oxidative stress.
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