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A Novel Phage Protein Mediates the Virus's Removal from Bacterial Chromosomes
Author(s) -
Liza Gross
Publication year - 2006
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.0040213
Subject(s) - biology , bacterial protein , virus , phage display , virology , genetics , bacterial virus , bacterial artificial chromosome , bacteriophage , bacteria , computational biology , microbiology and biotechnology , genome , gene , escherichia coli , antibody
Long before anyone realistically entertained the notion of engineering transgenic corn, cloned dogs, or designer babies, scientists looked for clues to the fundamental properties of life in much simpler organisms. Studies in one such organism—bacteria-infecting viruses called bacteriophages, or phages—produced some of the most important discoveries of molecular biology: identifying DNA as the genetic material, elucidating the mechanism of genome replication, and revealing the power of recombinant DNA, the backbone of genetic engineering.

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