Neuromedin U and Its Putative Drosophila Homolog hugin | Zendy

Christoph Melcher | Zendy; Rüdiger Bader | Zendy; Steffen Walther | Zendy; Oleg Simakov | Zendy; Michael J. Pankratz | Zendy

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Neuromedin U and Its Putative Drosophila Homolog hugin

Author(s) -

Christoph Melcher,

Rüdiger Bader,

Steffen Walther,

Oleg Simakov,

Michael J. Pankratz

Publication year - 2006

Publication title -

plos biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.127

H-Index - 271

eISSN - 1545-7885

pISSN - 1544-9173

DOI - 10.1371/journal.pbio.0040068

Subject(s) - biology , drosophila (subgenus) , drosophila melanogaster , evolutionary biology , genetics , zoology , gene

We recently provided a molecular, neuroanatomical, and behavioral analyses of neurons expressing the neuropeptide gene hugin in Drosophila [1]. hugin-expressing neurons appear to comprise a neural circuitry in the brain that modulates feeding behavior in response to gustatory and nutrient signals. One of the questions arising from this study was whether a mammalian homolog of hugin exists. We argue here that a mammalian homolog of Drosophila hugin may be neuromedin U (NmU).

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