Open AccessYeast Prions: Protein Aggregation Is Not Enough
Author(s) -
Michael Y. Sherman
Publication year - 2004
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.0020125
Subject(s) - biology , yeast , protein aggregation , saccharomyces cerevisiae , computational biology , genetics
Although many proteins -- both damaged and normal -- have a tendency to aggregate, only some are capable of dividing and propagating. What does it take to turn a protein aggregate into an infectious prion?
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