Open AccessRNAi Therapeutics: How Likely, How Soon?
Author(s) -
Richard Robinson
Publication year - 2004
Publication title -
plos biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.127
H-Index - 271
eISSN - 1545-7885
pISSN - 1544-9173
DOI - 10.1371/journal.pbio.0020028
Subject(s) - biology , rna interference , computational biology , genetics , evolutionary biology , gene , rna
RNA interference (RNAi) is used in the lab to silence virtually any gene. Previously, antisense and ribozymes were successful in the lab, but have been disappointing in the clinic. Will RNAi succeed where these two have not?
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