More Fibrosis and Thrombotic Complications but Similar Expression Patterns of Markers for Coagulation and Inflammation in Symptomatic Plaques from DM2 Patients | Zendy

Dirkje W. Sommeijer | Zendy; Aida Beganović | Zendy; Casper G. Schalkwijk | Zendy; Hanneke J Ploegmakers | Zendy; Chris M. van der Loos | Zendy; Benien E. van Aken | Zendy; Hugo Ten Cate | Zendy; Allard C. van der Wal | Zendy

Open Access

More Fibrosis and Thrombotic Complications but Similar Expression Patterns of Markers for Coagulation and Inflammation in Symptomatic Plaques from DM2 Patients

Author(s) -

Dirkje W. Sommeijer,

Aida Beganović,

Casper G. Schalkwijk,

Hanneke J Ploegmakers,

Chris M. van der Loos,

Benien E. van Aken,

Hugo Ten Cate,

Allard C. van der Wal

Publication year - 2004

Publication title -

journal of histochemistry and cytochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 124

eISSN - 1551-5044

pISSN - 0022-1554

DOI - 10.1369/jhc.3a6207.2004

Subject(s) - medicine , fibrosis , inflammation , immunostaining , tissue factor , pathological , pathology , diabetes mellitus , coagulation , fibrinogen , risk factor , immunohistochemistry , endocrinology

One of the possible pathological mechanisms behind the increased vascular injury in diabetes mellitus type 2 (DM2) is the formation of advanced glycation end products (AGEs). The aim of this study was to investigate whether the presence of AGEs and specific markers for coagulation and inflammation in symptomatic atherosclerotic plaques from DM2 patients differs from plaques from nondiabetics.

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