Nonlinear optical contrast enhancement for optical coherence tomography | Zendy

Claudio Vinegoni | Zendy; Jeremy S. Bredfeldt | Zendy; Daniel L. Marks | Zendy; Stephen A. Boppart | Zendy

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Nonlinear optical contrast enhancement for optical coherence tomography

Author(s) -

Claudio Vinegoni,

Jeremy S. Bredfeldt,

Daniel L. Marks,

Stephen A. Boppart

Publication year - 2004

Publication title -

optics express

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.394

H-Index - 271

ISSN - 1094-4087

DOI - 10.1364/opex.12.000331

Subject(s) - optical coherence tomography , optics , interferometry , coherence (philosophical gambling strategy) , raman scattering , heterodyne detection , second harmonic imaging microscopy , heterodyne (poetry) , optical tomography , nonlinear optics , second harmonic generation , physics , signal (programming language) , contrast (vision) , materials science , raman spectroscopy , laser , computer science , acoustics , programming language , quantum mechanics

We present a new interferometric technique for measuring Coherent Anti-Stokes Raman Scattering (CARS) and Second Harmonic Generation (SHG) signals. Heterodyne detection is employed to increase the sensitivity in both CARS and SHG signal detection, which can also be extended to different coherent processes. The exploitation of the mentioned optical nonlinearities for molecular contrast enhancement in Optical Coherence Tomography (OCT) is presented.

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