Laser-speckle-based detection of fluid pulsation in the presence of motion artifacts: in vitro and in vivo study | Zendy

M. Nemati | Zendy; Ralph Wijshoff | Zendy; J. Marco A. Stijnen | Zendy; Sjoerd van Tuijl | Zendy; J.W.M. Bergmans | Zendy; Nandini Bhattacharya | Zendy; H. P. Urbach | Zendy

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Laser-speckle-based detection of fluid pulsation in the presence of motion artifacts: in vitro and in vivo study

Author(s) -

M. Nemati,

Ralph Wijshoff,

J. Marco A. Stijnen,

Sjoerd van Tuijl,

J.W.M. Bergmans,

Nandini Bhattacharya,

H. P. Urbach

Publication year - 2013

Publication title -

optics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.524

H-Index - 272

eISSN - 1071-2763

pISSN - 0146-9592

DOI - 10.1364/ol.38.005334

Subject(s) - speckle pattern , optics , oscillation (cell signaling) , amplitude , signal (programming language) , laser , physics , speckle imaging , computer science , chemistry , biochemistry , programming language

We have performed an in vitro and in vivo study, based on laser speckle contrast analysis, to detect fluid pulsation in the presence of artifacts caused by the relative motion between the sample and the illumination source. We observe that the pulsation signal is clearly detectable for a range of motion amplitudes and oscillation frequencies; however, for higher amplitudes and oscillation frequencies of motion, the signal, due to pulsation, becomes increasingly difficult to detect.

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