Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography | Zendy

Shuichi Makita | Zendy; Tapio Fabritius | Zendy; Yoshiaki Yasuno | Zendy

Open Access

Quantitative retinal-blood flow measurement with three-dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography

Author(s) -

Shuichi Makita,

Tapio Fabritius,

Yoshiaki Yasuno

Publication year - 2008

Publication title -

optics letters

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.524

H-Index - 272

eISSN - 1071-2763

pISSN - 0146-9592

DOI - 10.1364/ol.33.000836

Subject(s) - optics , doppler effect , blood flow , optical coherence tomography , materials science , laser doppler velocimetry , retinal , angiography , physics , medicine , radiology , ophthalmology , astronomy

Retinal blood flow quantification by retinal vessel segmentation with Doppler optical coherence angiography is presented. Vessel diameter, orientation, and position are determined in an en face vessel image and two representative cross-sectional flow images of the vessel. Absolute blood flow velocity is calculated with the help of the measured Doppler frequency shift and determined vessel angle. The volumetric flow rate is obtained with the position and the region of the vessel lumen. The volumetric blood flow rate of retinal arteries before and after a bifurcation is verified in a healthy human eye.

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